Danny Harding cracked an unbeaten 149 as Chadlington compiled 209-3 in 35 overs of their Division 1 clash.
Although Saqib Mohammed made an excellent 94 not out, Garsington fell an agonising five runs short.
Chadlington 27pts, Garsington 6
Minster Lovell squeezed past Shrivenham at home.
Having dismissed the visitors for 132, with Eddie Dunn taking 3-39, they eventually prevailed in the 34th of 36 overs by three wickets.
Minster Lovell 28, Shrivenham 5
Stonesfield stay second in Division 2 after a comfortable victory at home to Tetsworth.
With the wickets shared around, they shot out the opposition for 120 before Tim Wyatt (63no) saw his side home at 121-1.
Stonesfield 30, Tetsworth 2
Previous Division 3 front runners Witney Swifts slipped to defeat at Chesterton, who took over at the top as a result.
Replying to 116-5 off 25 overs, Chesterton knocked off the requirement for the loss of five wickets.
Chesterton 26, Witney Swifts 4
In another rain-reduced 25-over contest, Eynsham went down to a 89-run defeat at Cairns Fudge.
The hosts piled on 154-6, Steve Shaw blasting 41 and Andy Small 39 not out.
Three wickets apiece for James Robertson (3-8) and Steve Shaw (3-17) then limited Eynsham to 65-9.
Cairns Fudge 27, Eynsham 3
James Snow smashed 130 and Andrew Wingfield Digby 84 as Swinbrook amassed 264-4 at home to Britwell Salome in Division 4.
Jack Bullivant then took 4-21 as the visitors were dismissed for 163.
Swinbrook 30, Britwell Salome 8
Richard Nash top-scored with 52 in Charlbury’s 106-7 against Deddington.
It was not enough however, as Gerard Duncan (51no) saw his side home by seven wickets.
Charlbury 2nd 2, Deddington 27
In the only completed match in Division 5, Kil-kenny were routed for 55 as they crashed to a nine-wicket defeat to Risinghurst.
John Thompson, with 5-12, did the damage for Rising-hurst who reached the target in fewer than six overs, Rahul Venkat hitting a quick-fire 38.
Kilkenny 0, Risinghurst 29
Bampton battered 165-5 at home to Broughton & North Newington 2nd in Division 7.
Grant Print smashed 73 and Steve Sheppard 54 not out.
The visitors were then shot out for 78, Ady Brooksbank bagging 4-14 and Josh Norris 3-23.
Bampton 28, Broughton 2nd 3
Despite an unbeaten 49 from George Thorne, Combe 2nd struggled to 87-4 at Cowley Internationals 2nd in Division 8.
With 41 not out, Waheed Rehman then steered the hosts to a nine-wicket victory.
Cowley 2nd 27, Combe 2nd 1
Eynsham 2nd crashed to a 150-run defeat against Wootton & Boars Hill 2nd in the final of the Keith Crump Centenary Cup at Fringford.
Wootton racked up 243-5, thanks primarily to an undefeated 120 from man-of-the-match Rami Garrimella and a quick-fire 47 by skipper Marcus Charman.
Simon Steer then took 4-18 as the Eynsham innings stuttered to 93 all out.