Carterton went down to a 6-0 loss at Oxfordshire Senior Cup holders Ardley United in the first round on Saturday.
The visitors, who play in Hellenic League Division 1 East had no answer to their Premier Division opponents who eased to victory, with goals from Ricky Johnson, Luke Ingram, Ben Thomas Chris Jackson, Kieran Scott and Adam Beckett.
Reece Bayliss went closest for Carterton when his lobbed shot came back off a post.
Old Woodstock Town beat previously unbeaten Senior League side Oxford University Press 4-1 with a pair of penalties from Rob Keylock plus efforts from Jack Heap and Jack Dunmall.
North Leigh United lost 6-5 at fellow Hellenic League Thame United 6-5 in a penalty shoot-out after the visitors fought back to draw 1-1.
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